Abstract:
This  work  is  devoted  to  the  phytochemical  study  and  antioxidant  activity  of  the  species 
Asteriscus  graveolens  (Asteraceae)  endemic  to  the  Sahara  in  Algeria.   crude  extract  is 
prepared  by  hydroalcoholic  maceration  followed  by  liquid-liquid  extraction  with  solvents  of 
increasing  polarities  in  order  to  fractionate  the  crude  extract  into  three  phases.  The 
quantitative  analysis  of  the  extracts  is  carried  out  by  measuring  the  content  of  polyphenols, 
flavonoids  and  tannins.  The  estimation  of  the  antioxidant  activity  of  the  extracts  was 
evaluated by the DPPH and phosphomolybdate test. 
The results obtained show that the extracts of A. graveolens contain significant quantities of 
natural phenol and natural flavonoids but poor in natural tannin. The dichloromethane extract 
was richest in flavonoids and tannins, while the acetate extract was richest in tatal phenols. 
All  extracts  demonstrated  excellent  free  radical  scavenging  activity  where  ethyl  acetate 
extract demonstrated the best antioxidant activity via DPPH test with a value of IC50 =0.0042 
and total antioxidant activity with a value of  EC50 =0.0892. This activity may be due to the 
chemical  nature  of  the  compounds  present  in  these  extracts.  These  results  justify  the  use  of 
this plant in traditional medicine.