Etude de quelques paramètres biochimiques de la glande thyroïde dans la région de Ghardaïa

Abstract

The thyroid synthesizes hormones: T4 and T3, whose action is to regulate basal metabolism as well as tissue growth and maturation. For that these thyroid hormones be secreted according to the needs of the body, the pituitary gland secretes a regulatory hormone, which acts directly on the thyroid that is called: Thyroid Stimulin Hormone (TSH). The aim of this study is to monitor changes in thyroid hormones (TSH, T3, T4, Tg, anti-TPO and anti- Tg) in a male and female population originating from the Ghardaia region and accusing euthyroidism, hyperthyroidism and / or hypothyroidism. This study also aims to master the hormonal assay method (automated) based on ELISA technique (Enzyme Linked Immuno Sorbent Assay). In our study the plasma levels of T3 and T4 show a significant difference compared to healthy people. Serum T3 and T4 levels are decreased in people with hypothyroidism and high in those with hyperthyroidism. In some cases in our study it was noted that serum T3 levels and T4 is within the standards despite the disturbance of TSH levels this result shows that the Most of the population is on treatment that balances thyroid hormone levels. In terms of the population studied in Ghardaïa province, women are the most affected by different thyroid diseases compared to men and especially women frequently associated with hypothyroidism, female sex has been found to be a factor in risk for thyroid pathology. It is also noted in our study that the factor body mass index and emotional shock; Familial ATCD are factors ofrisk.